Description
Golden biscuit dough, savory sauce, melty cheese, and crispy pepperoni baked into a cozy, weeknight-friendly pizza casserole that satisfies like a slice—but eats like comfort food.
Ingredients
1 can refrigerated flaky or homestyle biscuit dough (16.3 oz)
1 cup pizza sauce
1 teaspoon dried oregano
1/2 teaspoon garlic powder
1/2 teaspoon onion powder
1 cup shredded whole-milk low-moisture mozzarella cheese
1/2 cup shredded provolone cheese
1/4 cup grated parmesan cheese
1/2 cup mini pepperoni or chopped sandwich pepperoni
1 tablespoon chopped fresh parsley or basil
Nonstick cooking spray or oil for greasing
Instructions
1. Preheat the oven to 350°F and lightly grease a 9×13-inch baking dish.
2. Cut the biscuits into quarters and arrange them evenly in the prepared dish.
3. Bake the biscuits for 8 minutes to partially cook and prevent sogginess.
4. While baking, combine pizza sauce with oregano, garlic powder, and onion powder.
5. Remove the dish from the oven and spread the seasoned sauce evenly over the biscuits.
6. Sprinkle mozzarella and provolone cheese over the top, then layer on the partially cooked pepperoni.
7. Return the casserole to the oven and bake for an additional 18–22 minutes, or until the cheese is bubbling and the biscuits are golden brown.
8. In the last 5 minutes, sprinkle parmesan over the top for added flavor and color.
9. Let the casserole rest for 5–10 minutes before serving to set the layers.
10. Finish with a sprinkle of chopped parsley or basil just before serving.
Notes
Partially baking the biscuit dough before layering keeps the bottom from getting soggy.
Mixing cheese types helps prevent rubbery texture and boosts flavor.
Reheat leftovers in a low oven covered with foil to preserve texture.
- Prep Time: 10 minutes
- Cook Time: 30 minutes
- Category: Casserole
- Method: Baking
- Cuisine: American
Nutrition
- Serving Size: 1 serving
- Calories: 410
- Sugar: 4g
- Sodium: 860mg
- Fat: 24g
- Saturated Fat: 10g
- Unsaturated Fat: 11g
- Trans Fat: 0g
- Carbohydrates: 35g
- Fiber: 2g
- Protein: 14g
- Cholesterol: 45mg
Keywords: bubble up pizza, biscuit pizza casserole, pepperoni casserole, easy pizza dinner